Human casein alpha s1 (CSN1S1) skews in vitro differentiation of monocytes towards macrophages
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چکیده
منابع مشابه
CYCLIC NUCLEOTIDES CONTROL DIFFERENTIATION OF HUMAN MONOCYTES INTO EITHER HIGHLY ACCESSORY CELLS OR MACROPHAGES
Human peripheral blood monocytes have been found to undergo a transitory state of high accessory activity before they fully become macrophages. Time kinetics were done to follow this accessory potential. Studying the regulation of accessory activity, we have found that monocyte derived accessory cells (m-AC) pass through two phases of development, both of which are adversely controlled by ...
متن کاملcyclic nucleotides control differentiation of human monocytes into either highly accessory cells or macrophages
human peripheral blood monocytes have been found to undergo a transitory state of high accessory activity before they fully become macrophages. time kinetics were done to follow this accessory potential. studying the regulation of accessory activity, we have found that monocyte derived accessory cells (m-ac) pass through two phases of development, both of which are adversely controlled by cycli...
متن کاملHydrogen peroxide metabolism in human monocytes during differentiation in vitro.
The capacity of human blood monocytes to secrete hydrogen peroxide (H2O2) and superoxide (O2-) was measured as the cells differentiated during 4 wk of culture. Morphologic transformation of monocytes into macrophages, epithelioid cells, and multinucleated giant cells accompanied a steady increase in the content of protein per cell, from 0.77 mg/10(7) cells on days 0 to 11.77 mg/10(7) cells on d...
متن کاملDifferential Expression of Alpha S1 Casein and Beta-Lactoglobulin Genes at Different Physiological stages of the Adani Goats Mammary Glands
Background: Milk proteins genes have been the focus of the researches as the candidate target genes that play a decisive role when animal breeding is desired.Objectives: In the present study, the transcriptional levels of Beta-lactoglobulin (BLG) and Alpha S1 casein (CSN1S1) genes were investigated during prenatal, milking and drying times in mammary glands of the Adani goats which showed...
متن کاملHuman Monocytes and Macrophages
PPD-sensitized monocytes and macrophages from tuberculin-positive subjects are both capable of inducing blastogenic transformation of autologous lymphocytes. Incorporation of thymidine-(3)H and morphological transformation were always greater in lymphocyte cultures containing macrophages than in those containing monocytes. More lymphocytes entered the first detectable S phase in cultures contai...
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ژورنال
عنوان ژورنال: BMC Immunology
سال: 2013
ISSN: 1471-2172
DOI: 10.1186/1471-2172-14-46